ESPE Abstracts

Background: It is hard to treat severe obese children only with diet and physical activity, psychological interventions are need.Objective and hypotheses: To examine the differences between courses of non-medicament treatment of severe obese children.Method: We examined 32 pubertal severe obese children BMI 31.2±0.8 kg/m2, 13.5±0.3 years. The newel (in Belarus) course of non-medicament treatment of obesity (die...

Background: Among alimentary factors leading to obesity in children, the main ones are: consumption of high-calorie foods with high content of carbohydrates and getting more calories during the second half of the day.Objective: To study feeding habits in children of different ages with alimentary obesity compared with normative values.Methods: We compared 3-day food diaries of 115 children with alimentary obesity with nutritional s...

Background: Serotonine transporter gene (SLC6A4) polymorphism is one of genetic aspects of appetite and mood disorders.Objective and hypotheses: To determine the frequencies of 5-HTTLPR locus in promotor part of serotonine transporter gene (SLC6A4) polymorphism in children with different forms of obesity.Method: We examined 191 pubertal obese children. Patients were divided: Group 1 (simple obesity) 143 children, 14.3±1.8 year...

Background: Polymorphic genes Val158Met gene catechol-O-metiltrasferaz (COMT) are used to be responsible for less neurotransmitters utilization.Objective and hypotheses: To determine the peculiarities of neurotransmitters levels in children with obesity and different genotypes of COMT gene.Method: We examined 191 pubertal obese children. Patients were divided: Group1 (simple obesity) 143 children, 14.3±1.8 years, 30.6±2.8...

Background: Obesity is a worldwide pathological epidemic. Children and adolescents are a major concern in this trend.Objective and hypotheses: To identify the dynamics of body composition in children with alimentary obesity in puberty.Methods: 105 children with alimentary obesity with BMI over 30 kg/m2 were examinated. Anthropometric parameters (height, weight, waist, and hip circumference (WC, CH)), BMI, biochemical par...

Background: Obesity is accompanied with the development of serious complications, including behavioural disorders. Obesity with impaired neuroendocrine status confirmed, but papers describing these interactions are a bit.Objective and hypotheses: To compare the state of neuroendocrine status in children with various forms of obesity and normal weight control to the evaluation of central hormonal regulators of energy balance.Method:...

Background: Congenital adiptical diabetes insipidus is rare condition in infancy. Immediate diagnosis and treatment is required to ensure normal development.Case report: A boy, from the 2nd pregnancy, 1st term delivery was born with weight 4480 g. Bottle feeding from the 1st months. Weight at 1st months – 4500 g, at 2nd – 5000 g. Until the first 2 months mother complained on child’s apathia, feeding problems, vomiting, weight stagnation. A...

Background: The relationship of obesity and emotional disorders is confirmed in many studies. It is known that one of the substances responsible for the emotional status is dopamine.Objective: To study the features of neuroendocrine status in obese children.Methods: We examined 285 children (206 obese, age 14.56±2 years, BMI 32.86±5.1 kg/m2; 79 normal weight (control), 14.51±2.2 years (P=0.95), 19...

Background: Emotional disorders are serious complications in obese children. Dopamine is known to be one of the neurotransmitters, which is in charge of such conditions.Aim: To determine neuroendocrine and psychological status in obese children.Methods: We examined 296 children in the Endocrinological Department of University Hospital (Minsk); group 1 – 206 obese children (simple obesity: 14.35±2 years; BMI 30.8±2.5 ...

Aim: To identify early risk factors of the development of alimentary obesity in adolescence.Methods: We analysed retrospectively 375 histories of development of adolescents: group 1 – 206 obese children (14.55±2.06 years, BMI 32.9±5.1 kg/m2), group 2 – 169 normal-weight patients (12.6±2.2 years (P=0.2); BMI 20.5±1.2 kg/m2 (P=0.0001)) from the University Hospital (Minsk). We collected a...